Despite Our Differences is the tenth studio album by the Indigo Girls, released in 2006.  　　 　　 　　John Metzger from MusicBox Online described Despite Our Differences as "the most infectious, pop-infused set that the duo ever has managed to concoct. In fact, its melodies, harmonies, and arrangements are so ingratiating that the album carries the weight of an instant classic."[citation needed] Thom Jurekof from Allmusic wrote: "part of an emotional journey as complete as can be. More relevant than anyone dared expect. It's accessible and moving and true. It's their own brand of rock & roll, hewn from over the years, that bears a signature that is now indelible. A moving, and utterly poetic offering."[citation needed] And David Sprague from Barnes and Noble called it "an emotional journey as complete as can be".[citation needed]  　　 　　 　　"Rock and Roll Heaven's Gate" features a guest appearance by Pink, and Brandi Carlile performs on "Last Tears."  　　 　　 　　The album opened at #44 on the Billboard charts.[citation needed]